“Us Up Here and Them Down There”
نویسندگان
چکیده
منابع مشابه
Build them up and break them down
Tight junctions (TJs) of cells expressing simple epithelial polarity have been extensively studied, but less is known about TJs of cells expressing complex polarity. In this paper we analyzed, TJs of four different lines, that form bile canaliculi (BC) and express typical hepatocyte polarity; WIF-B9, 11-3, Can 3-1, Can 10. Striking differences were observed in claudin expression. None of the ce...
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The development of careful quality assurance criteria assuring freedom from contamination in all aspects of sample recovery has opened the window to studies of a fascinating new microbial biome in the deep subsurface. Organisms have been recovered with unusual metabolic capabilities and a chemosynthetic lifestyle independent of the recent surface photosynthetically derived energy inputs. The pr...
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This is an exciting yet trying time for people living with neuromuscular diseases and those who care for them. The exciting aspect is that at last the advances in genetics and translational research have resulted in clinical trials testing novel compounds. Examples include the exon-skipping approaches in Duchenne Muscular Dystrophy (DMD). Resulting from a sophisticated understanding of the cons...
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T he main hurdle for genome sequencing projects these days is no longer the effort and cost of generating sequence data—which has become exponentially cheaper—but the capacity to analyse huge amounts of data and make sense of it. This endeavour is made harder by another problem that has begun to emerge over the past years: DNA contamination. Contamination impacts both sequence data generation, ...
متن کاملHere, There, and Everywhere
Cytologists have long observed that individual eukaryotic species segregate their chromosomes in one of two apparently different ways. Monocentric chromosomes attach to microtubules at a particular region (the centromere) and move toward the pole during anaphase with the centromere leading. In contrast, holocentric chromosomes bind to microtubules along their entire length and move broadside to...
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ژورنال
عنوان ژورنال: Urban Affairs Review
سال: 2016
ISSN: 1078-0874,1552-8332
DOI: 10.1177/1078087415601221